BGC > Produktsuche > Zofenopril-d5 calcium salt | 81938-43-4

Appearance	White to whitish crystalline powder
Identification	(1),(2),(3)Must complies with the enterprise standard
PH	6.0~7.0
Specific Optical Rotation	-65.0°～ -70.0°
Calcium salt	4.3%~4.6%
Cl	Not more than 0.01%
SO4	Not more than 0.04%
K	Not more than 0.05%
Loss on drying	Not more than 0.5％
Heavy metals	Not more than 20ppm
Total related substances	Not more than 1.0%
Isomers	Not more than0.5%
Methanol	Not more than 0.3%
Acetonitrile	Not more than 0.041%
Pyridine	Not more than 0.02%
Assay On Dried Basis	Not less than 98.5％

Molecular Formula: C44H44CaN2O8S4
Molecular Weight: 897.16676
Hazard Symbols: N
UN Number: UN 3077 9 / PGIII
WGKGermany: 3

Description:
Zofenopril Calcium is an antioxidant and acts as an angiotensin-converting enzyme (ACE) inhibitor. lt is also an inhibitor of PEPT2, the predominant peptide transporter in kidney and choroid plexus. lt is a pro-drug designed to undergo metabolic hydrolysis yielding the active free sulfhydryl compound zofenoprilat. lt promotes the regeneration of peripheral nerve injuries in rat models. lt increases SR calcium cycling and stimulates active calcium uptake into the SR. It was developed by the Bristol Myers Squibb Company.

• Molecular Weight:897.17
• Boiling Point:646.3ºC at 760 mmHg
• Melting Point:>250ºC
• Purity:95%

Molecular Formula:
C44H44CaN2O8S4
Canonical SMILES:
CC(CSC(=O)C1=CC=CC=C1)C(=O)N2CC(CC2C(=O)[O-])SC3=CC=CC=C3.CC(CSC(=O)C1=CC=CC=C1)C(=O)N2CC(CC2C(=O)[O-])SC3=CC=CC=C3.[Ca+2]
InChI:
InChI=1S/2C22H23NO4S2.Ca/c2*1-15(14-28-22(27)16-8-4-2-5-9-16)20(24)23-13-18(12-19(23)21(25)26)29-17-10-6-3-7-11-17;/h2*2-11,15,18-19H,12-14H2,1H3,(H,25,26);/q;;+2/p-2/t2*15-,18+,19+;/m11./s1
InChIKey:
NSYUKKYYVFVMST-LETVYOFWSA-L
Solubility:
10 mM in DMSO
Appearance:
White to Off-White Solid
Application:
Zofenopril Calcium promotes the regeneration of peripheral nerve injuries in rat models. lt increases SR calcium cycling and stimulates active calcium uptake into the SR.
Storage: -20°C Freezer
Synonyms:
SQ26991; SQ 26991; SQ-26991; (4S)-N-[3-(benzoylsulfanyl)-2(s)-methylpropionyl]-4-(phenylsulfanyl)-l-proline calcium salt;[1(S),4(S)]-1-(3-Mercapto-2-methyl-1-oxopropyl)-4-phenyl-thio-L-proline-S-benzoyl Ester Calcium Salt;[(4S)-(2S)-3-(benzoylthio)-2-methylpro-pionyl-4-(phenylthio)-L-prolinelcalcium;Calcium;(2S,4S)-1-[(2S)-3-benzoylsulfanyl-2-methylpropanoyl]-4-phenylsulfanylpyrrolidine-2-carboxylate

Smile code:
O=C([O-])[C@H]1N(C([C@H](C)CSC(C2=CC=CC=C2)=O)=O)C[C@@H](SC3=CC=CC=C3)C1.O=C([O-])[C@H]4N(C([C@H](C)CSC(C5=CC=CC=C5)=O)=O)C[C@@H](SC6=CC=CC=C6)C4.[Ca+2]
MDL Number:
MFCD08704648
Purity :
98%
Available in stock:
10.212 g